DRUGS OF ABUSE

graphic, drug, statistic DRUGS OF ABUSE

The abuse of alcohol and drugs is a growing problem for today’s society which has wide reaching effects on the user, their family, the workplace and for a country’s health system. In order to help deal with this problem high quality, accurate drug screening tests are essential. MeDia Diagnostics provides a comprehensive range of ten drugs of abuse testing assays which offer a  range of benefits including:

ü Renowned methodology - all the MeDia Diagnostics drugs of abuse tests are homogenous enzyme immunoassays, with the exception of ethanol which is an enzymatic assay

ü Excellent correlation - with Gas Chromatography/ MassSpectrometry (GC/MS) methodology

ü Liquid ready-to-use reagents - for convenience and easeof-use

ü Choice of results format - qualitative or quantitative results are possible

ü Extensive measuring ranges - enabling the presence or absence of a drug to be detected

ü Liquid calibrators and controls - with multi-analyte products available for selected tests

ü Applications available - with instrument specific settings for a wide range of analysers

ü Compatible with SciTeck® adulteration applications helping ensure that any samples which may have been tampered with do not evade detection

List of Drugs of abuse monitoring test kits

-Amphetamines

-Barbiturates

-Benzodiazepines

-Cannabinoids

-Cocaine

-Ecstasy

-EDDP

-Ethanol

-Methadone

-Opiates

 

 

Amphetamines and Methamphetamines

The main role of Apolipoprotein A-I (Apo A-I) is in the removal of excess cholesterol from extra-hepatic tissues. Like HDL Cholesterol Apo A-I can be described as non-atherogenic showing an inverse relationship to cardiovascular disease risk. Individuals with cardiovascular disease generally have reduced levels of Apo A-I

and increased levels of Apo B.

The MeDia Diagnostics Apo A-I assay is based on an immunoturbidimetric method. All reagents are liquid ready-to-use and suitable for use on a wide range of chemistry analysers.

Key Features

• Homogenous enzyme immunoassay

• 97.5% correlation with GC/MS values

• Liquid ready-to-use format

• Included in MeDia Diagnostici multi-analyte drugs of abuse control and calibrator products

• On board stability of 28 days at approximately +10°C

• Multiple analyser applications available

AMPHETAMINES
AMPHETAMINES insert kit
AMP-EIA-158-BT-CE- IT-0-20032012.pdf
Documento Adobe Acrobat [472.8 KB]

Barbiturates

Barbiturates are central nervous system depressants which are used therapeutically as sedatives and anticonvulsants. There are a number of risks associated with the recreational consumption of barbiturates including lowered blood pressure, fatigue, impaired judgement and respiratory depression.

Key Features

• Homogenous enzyme immunoassay

• 93.3% correlation with GC/MS values

• Liquid ready-to-use format

• Included in MeDia Diagnostici multi-analyte drugs of abuse control and calibrator products

• On board stability of 28 days at approximately +10°C

• Multiple analyser applications available

Benzodiazepines

Benzodiazepines have a range of physio-chemical and pharmacological properties. When benzodiazepines are used recreationally the effects can be sedating and intoxicating, however the consumption of these drugs can lead to a number of problems such as physical and psychological dependence, depression, anxiety and insomnia.

Key Features

• Homogenous enzyme immunoassay

• 93.7% correlation with GC/MS values

• Liquid ready-to-use format

• Included in MeDia Diagnostici multi-analyte drugs of abuse control and calibrator products

• On board stability of 28 days at approximately +10°C

• Multiple analyser applications available

Cannabinoids

Cannabinoids are the compounds that produce the effects associated with marijuana consumption. Marijuana abuse produces mixed calming and stimulating effects but the consequences associated with the use of this drug can include memory and concentration problems and increased heart rate. The chronic use of marijuana may cause psychological damage

 

Key Features

• Homogenous enzyme immunoassay

• 93.3% correlation with GC/MS values

• Liquid ready-to-use format

• Dedicated cannabinoids controls and calibrator available

• On board stability of 28 days at approximately +10°C

• Multiple analyser applications available

CANNABINOIDS
CANNABINOIDS insert kit
THC-EIA-148-BT-CE- IT-1-31072013.pdf
Documento Adobe Acrobat [477.1 KB]

Cocaine Metabolite

Cocaine is a central nervous system stimulant whose consumption can have effects such as euphoria, alertness and hyperactivity. However, cocaine abuse can also produce numerous undesirable side effects including cardiac toxicity and ehavioural responses such as paranoia, hallucinations and severe psychosis.

 

Key Features

• Homogenous enzyme immunoassay

• 99.3% correlation with GC/MS values

• Liquid ready-to-use format

• Dedicated cannabinoids controls and calibrator available

• On board stability of 28 days at approximately +10°C

• Multiple analyser applications available

COCAINE
COCAINE insert kit
THC-EIA-148-BT-CE- IT-1-31072013.pdf
Documento Adobe Acrobat [477.1 KB]

Ecstasy

Ecstasy drugs are a group of amphetamine derivatives, including MDMA, MDA and MDEA. Ecstasy drugs are popularly abused for their mood altering effects which can create feelings of euphoria. However, ecstasy can also cause the user to experience hallucinations, depression, cardiac arrhythmias and sleep disorders.

 

Key Features

• Homogenous enzyme immunoassay

• 99.3% correlation with GC/MS values

• Liquid ready-to-use format

• Dedicated cannabinoids controls and calibrator available

• On board stability of 28 days at approximately +10°C

• Multiple analyser applications available

ECSTASY
ECSTASY insert kit
THC-EIA-148-BT-CE- IT-1-31072013.pdf
Documento Adobe Acrobat [477.1 KB]

EDDP

EDDP is a methadone metabolite. Methadone is a prescribed opioid which is used to relieve chronic pain, as well as for the detoxification and treatment of narcotic or heroin addiction. EDDP testing is commonly carried out to assess whether  ndividuals receiving methadone therapy are complying with their treatment. Methadone abuse can have side effects such as hallucinations and changes in the user’s personality.

 

Key Features

• Homogenous enzyme immunoassay

• 95.0% correlation with GC/MS values

• Liquid ready-to-use format

• Dedicated EDDP controls and calibrator available

• Stable to expiry date at +2-8°C

• Multiple analyser applications available

METHADONE
METHADONE insert kit
THC-EIA-148-BT-CE- IT-1-31072013.pdf
Documento Adobe Acrobat [477.1 KB]

Ethanol

Ethyl alcohol is found in high concentrations in alcoholic beverages. Many people consume alcohol responsibly; however abuse of alcohol can lead to a loss of alertness, stupor, coma and over the long term, could lead to addiction.

Furthermore, drinking alcohol during pregnancy carries a heavy risk of permanent mental and physical defects in the child, known as foetal alcohol syndrome.

 

 

Key Features

• Enzymatic assay using NAD and alcohol dehydrogenase

• Liquid ready-to-use format

• Suitable for use with both urine and serum samples

• Dedicated ethanol calibrator and control set available

• Stable to expiry date at +2-8°C

• Multiple analyser applications available

Methadone

As highlighted previously, the primary medical application of methadone is in the detoxification and treatment of narcotic or heroin addiction. Illecit methadone consumption can have a number of side effects. The user may experience problems such as chronic fatigue, hallucinations, mood changes and insomnia.

Key Features

• Homogenous enzyme immunoassay

• 90.9% correlation with GC/MS values

• Liquid ready-to-use format

• Included inmulti-analyte drugs of abuse control and calibrator products

• Stable to expiry date at +2-8°C

• Multiple analyser applications available

METHADONE
METHADONE insert kit
THC-EIA-148-BT-CE- IT-1-31072013.pdf
Documento Adobe Acrobat [477.1 KB]

Opiates

Common opiates include morphine, codeine and heroin. Morphine and codeine are legal painkillers however they are frequently abused for their central nervous ystem effects. Recreational use of these drugs can have a number of negative side effects including seizures, insomnia and respiratory depression. The risks associated with heroin consumption are great. Heroin is highly addictive and when administered  Intravenously with non-sterile needles, there is the risk of contracting diseases such as HIV or hepatitis.

Key Features

• Homogenous enzyme immunoassay

• 91.9% correlation with GC/MS

• Liquid ready-to-use format

• Included in multi-analyte drugs of abuse control and

calibrator products

• On board stability of 28 days at approximately +10°C

• Multiple analyser applications available

OPIATES
OPIATES insert kit
THC-EIA-148-BT-CE- IT-1-31072013.pdf
Documento Adobe Acrobat [477.1 KB]

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